23andMe ASHG 2012 poster presentations

Here. From "Genome wide association study of sexual orientation in a large, web-based cohort" (pdf):
Our GWAS results did not identify any genetic loci reaching genomewide significance at p < 5 x 10-8 among men or women. Among men, the peak (non-significant) hit was in chromosome 8q12.3 (chr8:63532921 in NKAIN3, p= 7.1 x 10-8).
More interesting (if generally unsurprising) are the phenotypic associations:
We examined the correlation between sexual identity and ~1000 phenotypes already characterized in the 23andMe database through other surveys. These analyses are preliminary; we have not checked for outliers or confounders beyond what is listed in the methods. We replicated previous findings showing a positive association between lesbians and alcoholism, and between lesbians and gay men and several psychiatric conditions.
A commenter at the 23andMe blog:
The phenotypic information is interesting if I’m reading it correctly: Gay men are less likely to to have played common US sports, and are more likely to cry easily or to have had liposuction. Lesbians are less likely to shave their legs. Surprisingly, gay men are less likely to be atheist or agnostic.

1 comment:

  1. "The phenotypic information is interesting if I’m reading it correctly: Gay men are less likely to to have played common US sports, and are more likely to cry easily or to have had liposuction. Lesbians are less likely to shave their legs."

    Imagine that, our eyes are right much of the time, contrary to what the pc police would have us believe.

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