tag:blogger.com,1999:blog-227780861638767023.post236925551860759244..comments2024-01-27T00:27:45.851+00:00Comments on race/history/evolution notes: Northern European population structuren/ahttp://www.blogger.com/profile/02378473351485233448noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-227780861638767023.post-47115387992137333842011-08-05T13:45:11.055+01:002011-08-05T13:45:11.055+01:00Correction: between the northern populations, the ...Correction: between the northern populations, the FST estimate is -0.000013 (missed the negative sign). So, there is essentially no difference detectable using their combined marker set (combines 1 intragenic and 2 intergenic marker sets). Looking at Table 3, I notice that the 2 intergenic marker sets show very low levels of differentiation (FST 0.00009 and 0.00008) whereas the estimate with the intragenic marker set (from protein-coding genes, nonsynonymous or 'effective promoter alteration') is negative (-0.00017). The FST estimate estimate for southern vs. northern populations is also lower using the intragenic SNPs. For Augsburg/Schleswig-Hostein, the estimate is 0.00003 with a standard error of 0.00014. Each marker set only had ~70 SNPs. Using a larger commercial chip would improve these estimates.<br /><br />It will be nice when large samples from European populations are publicly available (preferably from villages or small towns). Some of the larger studies with European populations unfortunately don't provide FST tables (I also had no luck in getting one when contacting the authors).Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-227780861638767023.post-33887399829608968542011-07-12T18:36:12.561+01:002011-07-12T18:36:12.561+01:00Incidentally, a different study reports an FST of ...<i>Incidentally, a different study reports an FST of 0.00054 between samples from north-east and southern Germany [1], suggesting the British and north Germans may be slightly more similar than some German subpopulations are to each other (although the data may not be strictly comparable).</i><br /><br />There was another northern German population in the Steffens paper, from Schleswig-Holstein (northwestern Bundesland that borders Denmark). The FST measure between the southern sample (from Augsburg, Bavaria) and that from Schleswig-Holstein was 0.00017. (Between the 2 northern populations, FST was 0.000013).Anonymousnoreply@blogger.com